Risk factors for stroke and predictors of one-month mortality

Singapore Med J. 2002 Oct;43(10):517-21.


Background: Stroke is the third most common cause of death in Malaysia.The prevalence of risk factors and predictors of mortality of stroke in Malaysia are poorly understood.

Aim: To identify the prevalence of major risk factors for stroke and to determine predictors of one-month mortality.

Method: Prospective study of all stroke patients admitted to Penang Hospital between December 1998 and November 1999. All patients were subjected to brain CT. Predictors of one-month mortality: systolic and diastolic hypertension, hyperglycaemia, type of stroke, age > or = 70, poor Glasgow coma score (GCS) on admission and deterioration of score were assessed.

Results: A total of 246 (139 male and 107 female) patients were included. Median age was 65 years. Hypertension was the commonest risk factor (71.5%) followed by diabetes mellitus (40.2%) and hyperlipidaemia (37%). 74.8% of the cases were ischaemic in origin and 25.2% haemorrhagic. Mortality at one month was 20.3%. Using multivariate analysis and logistic regression, deterioration of GCS (OR = 46.04), poor GCS on admission (OR = 12.35) and haemorrhagic stroke (OR = 3.45) were independent predictors of one-month mortality.

Conclusion: Hypertension and diabetes mellitus are the commonest risk factors of stroke among patients admitted to a tertiary hospital in Malaysia. Significant predictors of one-month mortality include the admission GCS, deterioration of GCS and haemorrhagic stroke.

MeSH terms

  • Aged
  • Female
  • Glasgow Coma Scale
  • Humans
  • Intracranial Hemorrhages / complications
  • Malaysia / epidemiology
  • Male
  • Predictive Value of Tests
  • Prevalence
  • Prospective Studies
  • Risk Factors
  • Stroke / epidemiology*
  • Stroke / mortality*