Specular microscopy of human corneal endothelium in vivo

Am J Ophthalmol. 1976 Mar;81(3):319-23. doi: 10.1016/0002-9394(76)90247-6.


A clinical specular microscope used in the routine examination fo the corneal endothelium of 40 patients at high magnification, without inconvenience or discomfort to the patients, detected endothelial damage or disease that was not seen by slit-lamp examination. A statistically significant decrease (P less than .001) in the number of central endothelial cells with age was documented.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Cornea / cytology*
  • Endothelium / cytology
  • Humans
  • Microscopy
  • Middle Aged
  • Photography