Polarised migration: cofilin holds the front

Curr Biol. 2003 Feb 18;13(4):R128-30. doi: 10.1016/s0960-9822(03)00072-1.


Persistent cell locomotion is a key feature of eukaryotic cells responding to diverse physiological cues. New work now directly implicates ADF/cofilin proteins as essential regulators of polarised cell migration.

Publication types

  • Comment
  • Review

MeSH terms

  • Actin Depolymerizing Factors
  • Animals
  • Cell Movement / physiology*
  • Microfilament Proteins / physiology*


  • Actin Depolymerizing Factors
  • Microfilament Proteins