A randomized controlled trial of coil removal prior to treatment of pelvic inflammatory disease

Eur J Obstet Gynecol Reprod Biol. 2003 Mar 26;107(1):81-4. doi: 10.1016/s0301-2115(02)00342-1.

Abstract

Objective: To evaluate the effects of removing coils on the treatment of mild and moderate pelvic inflammatory disease (PID).

Methods: Of 126 women who had mild to moderate PID during coil usage, 60 were treated following coil removal and 66 without. Clinical symptoms, findings of gynecologic examination, erythrocyte sedimentation rates (mm/h), leukocyte counts (mm(-3)) were recorded before and after treatment and recovery rates of symptoms and findings were compared with Chi-square and Fisher's absolute Chi-square tests. Student's t-test was used for the comparison of mean sedimentation rates and leukocyte counts.

Results: Recovery rates of pelvic pain, purulent vaginal discharge, dysuria/frequency and dyspareunia and clinical improvements in abdominal and cervical tenderness were significantly higher (P<0.05) in the coil removed group.

Conclusions: Removing the coil before medical therapy, increases the rates of clinical improvement in mild to moderate PID.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents / therapeutic use
  • Ciprofloxacin / therapeutic use
  • Device Removal*
  • Doxycycline / therapeutic use
  • Female
  • Humans
  • Intrauterine Devices*
  • Leukocyte Count
  • Metronidazole / therapeutic use
  • Pelvic Inflammatory Disease / drug therapy*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Metronidazole
  • Ciprofloxacin
  • Doxycycline