Firefighting and risk of testicular cancer: results from a German population-based case-control study

Am J Ind Med. 2003 Mar;43(3):291-4. doi: 10.1002/ajim.10178.


Background: There is some evidence of an elevated risk for testicular cancer among firefighters.

Methods: We performed a population-based case-control study including 269 testicular cancer cases and 797 controls matching on age and region with a special focus on occupational exposures. Job tasks were coded according to the International Standard Classification of Occupations (ISCO 68). We used conditional logistic regression to calculate odds ratios (OR).

Results: Three controls (0.4%) and four cases (1.5%) ever worked as firefighters. Firefighters showed an increased odds of testicular cancer in the matched evaluation (OR = 4.3, 95% confidence interval (95% CI) 0.7-30.5). The adjustment for a history of cryptorchidism or family history of testicular cancer did not alter our results.

Conclusion: Although the association between firefighting and testicular cancer risk is based on only small numbers of exposed subjects in our study, the finding is consistent with a recent cohort study from New Zealand. Occupational hazards experienced by firefighters may increase the risk of testicular cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Case-Control Studies
  • Confidence Intervals
  • Fires*
  • Germany / epidemiology
  • Humans
  • Interviews as Topic
  • Logistic Models
  • Male
  • Middle Aged
  • Occupational Diseases / epidemiology*
  • Odds Ratio
  • Testicular Neoplasms / epidemiology*