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, 72 (2), 499-502

Confirmatory Evidence for Linkage of Relative Hand Skill to 2p12-q11

Confirmatory Evidence for Linkage of Relative Hand Skill to 2p12-q11

Clyde Francks et al. Am J Hum Genet.

Figures

Figure  1
Figure 1
a, PegQ distribution in 222 siblings with RD who appeared normal for this measure and were previously analyzed genomewide for linkage (black) and in 338 left-writing-handed brothers from whom the current study sample was drawn (gray). Positive scores indicate superior relative right hand skill; the positive mean in the reading-disabled siblings is characteristic of unselected populations, whereas the sample of left-handed writers had a negative mean. We selected as extreme left-handed “probands” those individuals whose PegQ scores were >1.5 SD below the normal population mean. b, Comparison of linkage to PegQ across 2p16-q14 in RD siblings (Francks et al. 2002) and the left-handed brothers of the present study. X-axis, genomic interval with markers shown; Y-axis, pointwise significance of linkage.

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