Bacterial infections, immune overload, and MMR vaccine. Measles, mumps, and rubella

Arch Dis Child. 2003 Mar;88(3):222-3. doi: 10.1136/adc.88.3.222.

Abstract

Combined measles, mumps, and rubella (MMR) vaccine did not increase the risk of hospitalisation with invasive bacterial infection in the three months after vaccination; rather there was a protective effect. These results provide no support for the concept of "immunological overload" induced by multiple antigen vaccinations, nor calls for single antigen vaccines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Infections / immunology*
  • Bacterial Infections / prevention & control
  • Child, Preschool
  • Female
  • Hospitalization
  • Humans
  • Male
  • Measles-Mumps-Rubella Vaccine / adverse effects
  • Measles-Mumps-Rubella Vaccine / immunology*
  • Pneumonia, Pneumococcal / immunology
  • Risk Factors

Substances

  • Measles-Mumps-Rubella Vaccine