Giant cell reparative granuloma of the occipital bone

Skeletal Radiol. 2003 Mar;32(3):151-5. doi: 10.1007/s00256-002-0563-3. Epub 2002 Dec 7.


Giant cell reparative granuloma (GCRG) is a non-neoplastic fibrous lesion with unevenly distributed multinucleated giant cells, areas of osseous metaplasia and hemorrhage. The small bones of the hands and feet are the most common sites, followed by the vertebral bodies and craniofacial bones. In the craniofacial bones GCRG has been reported in the temporal bone, in the frontal bone and paranasal sinus. However, to the best of our knowledge no case has been reported in the occipital bone. We report on the imaging findings and pathological features of a GCRG of the occipital bone and discuss the differential diagnosis of this entity in this particular location, especially with giant cell tumor because of the therapeutic and prognostic implications.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Bone Diseases / diagnosis*
  • Bone Diseases / epidemiology
  • Bone Diseases / pathology
  • Granuloma, Giant Cell / diagnosis*
  • Granuloma, Giant Cell / epidemiology
  • Granuloma, Giant Cell / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Occipital Bone / pathology*
  • Tomography, X-Ray Computed