[FDG-PET on the day after first chemotherapy in malignant lymphoma]

Nihon Igaku Hoshasen Gakkai Zasshi. 2002 Dec;62(14):839-42.
[Article in Japanese]

Abstract

Positron emission tomography using 18F-fluorodeoxyglucose (FDG-PE) was performed in four patients with non-Hodgkin's lymphoma on the day after initial chemotherapy, in an attempt to predict the effects of chemotherapy earlier than standard methods. Twelve regions displaying intense uptake on baseline FDG-PET were selected, and decreases in the rate for each region were calculated from standardized uptake values on the day following chemotherapy. Seven of the 12 regions demonstrated decrease rates of 60% or more, and two decreased by 100%. This study indicates that FDG-PET on the day after first chemotherapy seems to reflect the effect of chemotherapy on malignant lymphoma.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents / therapeutic use*
  • Drug Monitoring / methods*
  • Female
  • Fluorine Radioisotopes*
  • Fluorodeoxyglucose F18*
  • Humans
  • Lymphoma, Non-Hodgkin / diagnostic imaging*
  • Lymphoma, Non-Hodgkin / drug therapy*
  • Middle Aged
  • Predictive Value of Tests
  • Radiopharmaceuticals*
  • Time Factors
  • Tomography, Emission-Computed*
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • Fluorine Radioisotopes
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18