Clinical trial of glibornuride in diabetes

Br Med J. 1975 Aug 30;3(5982):514-5. doi: 10.1136/bmj.3.5982.514.


Glibornuride is an addition to the second-generation sulphonylureas, that has been shown in clinical trials to be effective and non-toxic. Twenty-three diabetics who were poorly controlled on other oral hypoglycaemic agents and seven newly diagnosed diabetics were treated with glibornuride. The efficacy and lack of toxicity of this drug was confirmed, but there was no evidence to suggest that it is significantly more potent than other sulphonylureas. It does not seem to represent a significant therapeutic advance.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Blood Glucose
  • Diabetes Mellitus / drug therapy*
  • Evaluation Studies as Topic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Sulfonylurea Compounds / therapeutic use*


  • Blood Glucose
  • Sulfonylurea Compounds