Measurement of angiotensin II in human plasma: technical modifications and practical experience

Clin Chim Acta. 1976 Mar 15;67(3):299-306. doi: 10.1016/0009-8981(76)90338-7.


This paper presents our experience in measurement of plasma angiotensin II concentration according to the method described by Düsterdieck, G. and McElwee, G. (1971) Eur. J. Clin. Invest. 2, 32-38. Certain technical modifications of the procedure have been worked out. For each individual plasma sample, the recovery across extraction and elution steps is determined by addition of radio-iodinated angiotensin II. A time-saving recycling elution procedure is described. Evidence for the clinical applicability of the modified method is presented.

MeSH terms

  • Adult
  • Angiotensin II / blood*
  • Angiotensin II / immunology
  • Chromatography, Ion Exchange
  • Humans
  • Hypertension / blood
  • Kidney Diseases / blood
  • Kidney Diseases / surgery
  • Middle Aged
  • Radioimmunoassay / methods
  • Renin / blood
  • Time Factors


  • Angiotensin II
  • Renin