Understanding mechanisms of novel gene expression in polyploids

Trends Genet. 2003 Mar;19(3):141-7. doi: 10.1016/s0168-9525(03)00015-5.


Polyploidy has long been recognized as a prominent force shaping the evolution of eukaryotes, especially flowering plants. New phenotypes often arise with polyploid formation and can contribute to the success of polyploids in nature or their selection for use in agriculture. Although the causes of novel variation in polyploids are not well understood, they could involve changes in gene expression through increased variation in dosage-regulated gene expression, altered regulatory interactions, and rapid genetic and epigenetic changes. New research approaches are being used to study these mechanisms and the results should provide a more complete understanding of polyploidy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biological Evolution
  • Gene Dosage
  • Gene Expression Regulation*
  • Genes, Plant
  • Genetic Variation
  • Genome, Plant
  • Models, Genetic
  • Plants / genetics*
  • Polyploidy*
  • Selection, Genetic