The membrane domain of SpoIIIE is required for membrane fusion during Bacillus subtilis sporulation

J Bacteriol. 2003 Mar;185(6):2005-8. doi: 10.1128/JB.185.6.2005-2008.2003.

Abstract

During Bacillus subtilis sporulation, SpoIIIE is required for both postseptational chromosome segregation and membrane fusion after engulfment. Here we demonstrate that SpoIIIE must be present in the mother cell to promote membrane fusion and that the N-terminal membrane-spanning segments constitute a minimal membrane fusion domain, as well as direct septal localization.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacillus subtilis / chemistry
  • Bacillus subtilis / cytology
  • Bacillus subtilis / physiology*
  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Cell Division
  • DNA, Bacterial / metabolism
  • Membrane Fusion / physiology*
  • Mutation
  • Spores, Bacterial / physiology

Substances

  • Bacterial Proteins
  • DNA, Bacterial
  • spore-specific proteins, Bacillus