Metastatic potential of dermatofibrosarcoma protuberans with fibrosarcomatous change

J Surg Oncol. 2003 Mar;82(3):201-8. doi: 10.1002/jso.10211.


Dermatofibrosarcoma protuberans (DFSP) is a relatively uncommon fibrohistiocytic tumor that is locally aggressive. DFSP is associated with frequent local recurrences but rarely metastasizes. It has been suggested that fibrosarcomatous change within a dermatofibrosarcoma protuberans (DFSP-FS) is associated with increased risk of local recurrence and distant metastases. Metastases remain rare, however, and are typically preceded by multiple local recurrences. We report a rare case of a DFSP-FS metastasis to the head of the pancreas without any preceding local recurrence.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Dermatofibrosarcoma / secondary*
  • Female
  • Fibrosarcoma / secondary*
  • Humans
  • Neoplasm Recurrence, Local
  • Pancreatic Neoplasms / secondary*
  • Risk Factors
  • Skin Neoplasms / pathology*