Myriads of protein families, and still counting

Genome Biol. 2003;4(2):401. doi: 10.1186/gb-2003-4-2-401. Epub 2003 Jan 28.


From the historical record of genome sequencing, we show that the rate of discovery of new families has remained constant over time, indicating that our knowledge of sequence space is far from complete.

Publication types

  • Letter

MeSH terms

  • Animals
  • Genome*
  • Humans
  • Proteins / genetics*
  • Sequence Analysis, DNA / methods


  • Proteins