Chemokine signaling: rules of attraction

Curr Biol. 2003 Mar 4;13(5):R192-4. doi: 10.1016/s0960-9822(03)00122-2.

Abstract

The chemokine SDF-1 and its receptor CXCR4 control cell migration in the immune and nervous systems. Recent studies in zebrafish have shown that SDF-1 and CXCR4 also guide the migration of germ cells and sensory organs of the lateral line.

MeSH terms

  • Animals
  • Chemokine CXCL12
  • Chemokines, CXC / metabolism*
  • Embryonic Induction / physiology*
  • Germ Cells / metabolism
  • Receptors, CXCR4 / metabolism
  • Zebrafish / embryology
  • Zebrafish / physiology

Substances

  • Chemokine CXCL12
  • Chemokines, CXC
  • Receptors, CXCR4