The neuropsychological test performance of drug-abusing patients: an examination of latent cognitive abilities and associated risk factors

Exp Clin Psychopharmacol. 2003 Feb;11(1):34-45. doi: 10.1037//1064-1297.11.1.34.


The purpose of this study was to examine the latent structure of neuropsychological abilities of drug-abusing patients. Four factors were identified in an exploratory factor analysis (N = 329) and a subsequent confirmatory factor analysis (N = 258): Executive Functioning, Verbal Ability, Memory, and Speed, Education, years of regular alcohol use, number of substance use dependence disorders, percentage of days of heavy drinking in the previous year, depression, familial alcoholism, premorbid level of cognitive functioning, liver functioning, and previous head injuries were identified as risk factors to these latent abilities.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Cognition / physiology*
  • Ethnicity
  • Family
  • Female
  • Health Status
  • Humans
  • Male
  • Neuropsychological Tests*
  • Psychiatric Status Rating Scales
  • Reading
  • Risk Factors
  • Socioeconomic Factors
  • Substance-Related Disorders / psychology*