Abstract
Ankylosing spondylitis is an inflammatory disorder affecting the axial skeleton and periphery. Symptoms can often be debilitating. Current therapy for the disease include physical therapy, non-steroidal anti-inflammatory drugs (NSAIDS, anti-rheumatic disease modifying drugs (DMARDS), and the newly developed biologic agents targeting tumor necrosis factor alpha (TNF-alpha). This paper will provide a comprehensive review of these treatments which focusing on evidence based medicine for the daily clinical practice of rheumatology.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
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Antidepressive Agents, Tricyclic / therapeutic use
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Antirheumatic Agents / therapeutic use*
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Diphosphonates / therapeutic use
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Humans
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Immunosuppressive Agents / metabolism
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Immunosuppressive Agents / therapeutic use
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Pamidronate
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Physical Therapy Modalities*
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Spondylitis, Ankylosing / therapy*
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Thalidomide / metabolism
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Thalidomide / therapeutic use
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Tumor Necrosis Factor-alpha / metabolism
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Antidepressive Agents, Tricyclic
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Antirheumatic Agents
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Diphosphonates
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Immunosuppressive Agents
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Tumor Necrosis Factor-alpha
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Thalidomide
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Pamidronate