The treatment of ankylosing spondylitis

Clin Exp Med. 2003 Feb;2(4):159-65. doi: 10.1007/s102380300000.

Abstract

Ankylosing spondylitis is an inflammatory disorder affecting the axial skeleton and periphery. Symptoms can often be debilitating. Current therapy for the disease include physical therapy, non-steroidal anti-inflammatory drugs (NSAIDS, anti-rheumatic disease modifying drugs (DMARDS), and the newly developed biologic agents targeting tumor necrosis factor alpha (TNF-alpha). This paper will provide a comprehensive review of these treatments which focusing on evidence based medicine for the daily clinical practice of rheumatology.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Antidepressive Agents, Tricyclic / therapeutic use
  • Antirheumatic Agents / therapeutic use*
  • Diphosphonates / therapeutic use
  • Humans
  • Immunosuppressive Agents / metabolism
  • Immunosuppressive Agents / therapeutic use
  • Pamidronate
  • Physical Therapy Modalities*
  • Spondylitis, Ankylosing / therapy*
  • Thalidomide / metabolism
  • Thalidomide / therapeutic use
  • Tumor Necrosis Factor-alpha / metabolism

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antidepressive Agents, Tricyclic
  • Antirheumatic Agents
  • Diphosphonates
  • Immunosuppressive Agents
  • Tumor Necrosis Factor-alpha
  • Thalidomide
  • Pamidronate