Solitary fibrous tumour of the nasal cavity and paranasal sinuses

Acta Otolaryngol. 2003 Jan;123(1):71-4. doi: 10.1080/003655402000028052.

Abstract

Objective: Solitary fibrous tumour (SFT) is an uncommon unilateral benign lesion that usually arises from the pleura. Recently, SFT has been described in many other locations, such as the mediastinum, head and neck, orbit and urogenital system. To date, only 21 cases of SFT arising from the nasal cavity and paranasal sinuses have been reported in the literature.

Material and methods: We describe a case of SFT localized in the right nasal cavity with extension to the right ethmoid and sphenoid sinuses in a 43-year-old man who presented with a 6-month history of unilateral right-sided nasal obstruction, rhinorrhoea and recurrent epistaxis.

Results: CT showed a large mass arising from the right anterior ethmoid and sphenoid sinuses. Histopathologically, the lesion consisted of a non-encapsulated mass with spindle-shaped cells within a collagenous stroma. Definitive diagnosis was obtained by means of immunohistochemical analysis, which showed vimentin and CD34 cells.

Conclusion: The tumour was removed by endoscopic sinus surgery, and the patient remained free of tumour after 12 months of follow-up.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antigens, CD34 / analysis
  • Biomarkers, Tumor / analysis
  • Diagnosis, Differential
  • Endoscopy
  • Ethmoid Sinus* / pathology
  • Ethmoid Sinus* / surgery
  • Humans
  • Male
  • Mesothelioma / diagnosis*
  • Mesothelioma / pathology
  • Mesothelioma / surgery
  • Nose Neoplasms / diagnosis*
  • Nose Neoplasms / pathology
  • Nose Neoplasms / surgery
  • Paranasal Sinus Neoplasms / diagnosis*
  • Paranasal Sinus Neoplasms / pathology
  • Paranasal Sinus Neoplasms / surgery
  • Sphenoid Sinus* / pathology
  • Sphenoid Sinus* / surgery
  • Tomography, X-Ray Computed
  • Vimentin / analysis

Substances

  • Antigens, CD34
  • Biomarkers, Tumor
  • Vimentin