Molecular identification of the Na+-activated K+ channel

Neuron. 2003 Mar 6;37(5):727-8. doi: 10.1016/s0896-6273(03)00119-3.


Progress in understanding sodium-activated potassium channels (K(Na)), suggested to function in excitable cells both during physiological conditions and protectively during hypoxia, has been limited by their unknown molecular identity. In this issue of Neuron, Salkoff and coworkers now show that members of the Slo gene family, Slo2.1 and Slo2.2, encode functional K(Na) channels.

Publication types

  • Comment

MeSH terms

  • Animals
  • Potassium Channels / biosynthesis*
  • Potassium Channels / genetics*
  • Sodium / pharmacology


  • Potassium Channels
  • Sodium