Evaluation of the anti-microbial and anti-inflammatory activities of the medicinal plants Dodonaea viscosa, Rumex nervosus and Rumex abyssinicus

Fitoterapia. 2003 Feb;74(1-2):139-43. doi: 10.1016/s0367-326x(02)00315-5.

Abstract

The crude extracts of the leaves of Dodonaea viscosa and Rumex nervosus as well as of the root of Rumex abyssinicus were tested for anti-microbial and anti-inflammatory activities. It was observed that the three plants possess antibacterial activity against Streptococcus pyogenes and Staphylococcus aureus and strong activity against Coxsackie virus B3 and influenza A virus. In contrast, none of them exhibited anti-fungal activity. The anti-inflammatory activity test results verified that only R. abyssinicus inhibited the synthesis of prostaglandin (PG) E(2).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Infective Agents / administration & dosage
  • Anti-Infective Agents / pharmacology*
  • Anti-Infective Agents / therapeutic use
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / pharmacology*
  • Anti-Inflammatory Agents / therapeutic use
  • Cell Line, Tumor / drug effects
  • Dose-Response Relationship, Drug
  • Gram-Negative Bacteria / drug effects
  • Gram-Positive Bacteria / drug effects
  • HeLa Cells / drug effects
  • Humans
  • Macrophages / drug effects
  • Mice
  • Mitosporic Fungi / drug effects
  • Phytotherapy*
  • Plant Extracts / administration & dosage
  • Plant Extracts / pharmacology*
  • Plant Extracts / therapeutic use
  • Plant Leaves
  • Plant Roots
  • Rumex*
  • Sapindaceae*

Substances

  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Plant Extracts