Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma

Chest. 2003 Mar;123(3 Suppl):422S-4S. doi: 10.1378/chest.123.3_suppl.422s.
No abstract available

MeSH terms

  • Animals
  • Asthma / complications*
  • Asthma / physiopathology
  • Cell Physiological Phenomena / drug effects*
  • Disease Models, Animal
  • Fibroblasts / drug effects*
  • Fibroblasts / physiology
  • In Vitro Techniques
  • Interleukin-13 / pharmacology*
  • Lung / drug effects*
  • Lung / physiopathology
  • Myofibrils / drug effects*
  • Myofibrils / physiology
  • Pulmonary Fibrosis / etiology*
  • Pulmonary Fibrosis / physiopathology
  • Rats
  • Rats, Sprague-Dawley
  • Signal Transduction / drug effects*
  • Signal Transduction / physiology
  • Transcriptional Activation / drug effects*
  • Transcriptional Activation / physiology

Substances

  • Interleukin-13