Catastrophic antiphospholipid syndrome complicating orthotopic liver transplantation

Lupus. 2003;12(2):140-3. doi: 10.1191/0961203303lu278cr.


Catastrophic antiphospholipid syndrome (CAPS) is an acutely devastating situation characterized by widespread thrombotic microangiopathy in the presence of elevated titers of antiphospholipid antibodies. We describe a 57-year old woman who underwent liver transplantation for primary sclerosing cholangitis and developed this malignant variant of the antiphospholipid syndrome.

Publication types

  • Case Reports

MeSH terms

  • Antiphospholipid Syndrome / etiology*
  • Cholangitis, Sclerosing / surgery
  • Female
  • Humans
  • Liver Transplantation / adverse effects*
  • Middle Aged
  • Postoperative Complications*