Role of bacteria and HLA-B27 in the pathogenesis of reactive arthritis

Rheum Dis Clin North Am. 2003 Feb;29(1):21-36, v-vi. doi: 10.1016/s0889-857x(02)00082-0.

Abstract

Strictly speaking, "reactive arthritis" is a conventional term with no study-verified definition. This review will focus on the type of arthritis that is induced by the following species: Chlamydia, Shigella, Salmonella, Yersinia, and Campylobacter. The types of arthritis caused by these pathogens share a clinical pattern that is common in the spondyloarthropathies, especially undifferentiated spondyloarthropathy and Reiter's syndrome. All these diseases, including ankylosing spondylitis, must also share major pathogenetic pathways.

Publication types

  • Review

MeSH terms

  • Arthritis, Reactive / complications
  • Arthritis, Reactive / immunology*
  • Arthritis, Reactive / microbiology*
  • Arthritis, Reactive / physiopathology
  • Campylobacter Infections / complications
  • Campylobacter Infections / immunology
  • Campylobacter Infections / physiopathology
  • Cell Communication
  • Chlamydia Infections / complications
  • Chlamydia Infections / immunology*
  • Chlamydia Infections / physiopathology
  • Chlamydia trachomatis / immunology
  • Chlamydia trachomatis / pathogenicity
  • Enterobacteriaceae Infections / complications
  • Enterobacteriaceae Infections / immunology
  • Enterobacteriaceae Infections / physiopathology
  • HLA-B27 Antigen / immunology*
  • Humans
  • T-Lymphocytes / physiology*

Substances

  • HLA-B27 Antigen