Vitamin B12 deficiency: a case report of ongoing cutaneous hyperpigmentation

Cutis. 2003 Feb;71(2):127-30; quiz 138-40.


We describe an interesting case of a man with recurrent cutaneous and hematologic manifestations of vitamin B12 deficiency. In this deficiency, the skin, central nervous system, blood, and blood-forming tissues are commonly involved. We describe an overview of vitamin B12 deficiency and the successful treatment of a patient's ongoing cutaneous hyperpigmentation.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Hyperpigmentation / blood
  • Hyperpigmentation / drug therapy
  • Hyperpigmentation / etiology
  • Male
  • Middle Aged
  • Recurrence
  • Vitamin B 12 / therapeutic use
  • Vitamin B 12 Deficiency / drug therapy*
  • Vitamin B 12 Deficiency / etiology*


  • Vitamin B 12