Increasing incidence of endometrial cancer in the United States

N Engl J Med. 1976 Jun 3;294(23):1259-62. doi: 10.1056/NEJM197606032942303.

Abstract

Data from eight areas in the United States served by population-based cancer reporting systems indicate that, after many years of relative stability, incidence rates of endometrial cancer have risen sharply in the 1970's. In some areas the amount of the increase has exceeded 10 per cent per year. The incidence among middle-aged women has changed most (by 40 to 150 per cent between 1969 and 1973, depending on the area), but rates have increased in younger women and the elderly as well.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenocarcinoma / chemically induced
  • Adenocarcinoma / epidemiology
  • Adult
  • Age Factors
  • Aged
  • Androstenedione / metabolism
  • Contraceptives, Oral / adverse effects
  • Estrogens / adverse effects
  • Estrogens / metabolism
  • Estrone / metabolism
  • Female
  • Humans
  • Menopause
  • Middle Aged
  • Obesity / metabolism
  • United States
  • Uterine Neoplasms / chemically induced
  • Uterine Neoplasms / epidemiology*
  • Uterine Neoplasms / etiology

Substances

  • Contraceptives, Oral
  • Estrogens
  • Estrone
  • Androstenedione