Suppression of malignancy in human cells

Nature. 1976 Mar 4;260(5546):17-20. doi: 10.1038/260017a0.


Fusion between malignant and normal human cells results in the suppression of malignancy as measured by tumour formation. Malignant-malignant hybrids retain their malignant character. The human cell system has advantages for the study of the control of malignancy.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Fibroblasts
  • Genes, Recessive
  • HeLa Cells
  • Humans
  • Hybrid Cells*
  • Karyotyping
  • Neoplasms, Experimental / genetics*
  • Neoplasms, Experimental / pathology
  • Time Factors