Human metapneumovirus in severe respiratory syncytial virus bronchiolitis

Emerg Infect Dis. 2003 Mar;9(3):372-5. doi: 10.3201/eid0903.020289.


Reverse transcription-polymerase chain reaction was used to detect segments of the M (matrix), N (nucleoprotein), and F (fusion) genes of human metapneumovirus in bronchoalveolar fluid from 30 infants with severe respiratory syncytial virus bronchiolitis. Seventy percent of them were coinfected with metapneumovirus. Such coinfection might be a factor influencing the severity of bronchiolitis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bronchiolitis, Viral / complications
  • Bronchiolitis, Viral / virology*
  • Bronchoalveolar Lavage Fluid / virology*
  • Genome, Viral
  • Humans
  • Infant
  • Metapneumovirus / genetics*
  • Metapneumovirus / isolation & purification
  • Paramyxoviridae Infections / complications*
  • Respiratory Syncytial Virus Infections / complications
  • Respiratory Syncytial Virus Infections / virology*