Persistence of virus-reactive serum immunoglobulin m antibody in confirmed west nile virus encephalitis cases

Emerg Infect Dis. 2003 Mar;9(3):376-9. doi: 10.3201/eid0903.020531.


Twenty-nine laboratory-confirmed West Nile virus (WNV encephalitis patients were bled serially so that WNV-reactive immunoglobulin (Ig) M activity could be determined. Of those patients bled, 7 (60%) of 12 had anti-WNV IgM at approximately 500 days after onset. Clinicians should be cautious when interpreting serologic results from early season WNV IgM-positive patients.

MeSH terms

  • Aged
  • Antibodies, Viral / blood*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin M / blood*
  • Male
  • Middle Aged
  • West Nile Fever / blood
  • West Nile Fever / immunology*


  • Antibodies, Viral
  • Immunoglobulin M