Factors associated to lifestyle and risk of adult onset asthma

Respir Med. 2003 Mar;97(3):273-80. doi: 10.1053/rmed.2003.1419.


Background: Asthma prevalence has been increasing especially in developed countries. The change seems to be associated with changes in lifestyle. We have made a prospective study to assess the effect of lifestyle factors, including smoking, educational level, physical activity and obesity on adult onset asthma.

Methods: A population of 10,597 adult twins, initially free of asthma was followed for 9 years. The main outcome measure was questionnaire-based report of physician diagnosed asthma. Logistic regression was used to estimate the risk of asthma predicted by lifestyle factors, with adjustment for atopy and respiratory symptoms.

Results: Obesity at baseline increased asthma risk (multivariable adjusted OR = 3.00, 95% CI: 1.64-5.50 for those with BMI > or = 30 compared to those with normal weight BMI: 20-24.99). Taller height was associated to lower asthma incidence. Leisure time physical activity had a slightly protective effect on asthma risk among men (P for trend = 0.037) while smoking and education did not have significant effects on the risk of adult onset asthma.

Conclusions: Obesity was associated to the risk of adult onset asthma, while short height and low leisure time physical activity can be considered as other potential risk factors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Twin Study

MeSH terms

  • Adult
  • Asthma / epidemiology
  • Asthma / etiology*
  • Body Mass Index
  • Cohort Studies
  • Finland / epidemiology
  • Humans
  • Life Style*
  • Middle Aged
  • Obesity / complications
  • Prospective Studies
  • Risk Factors