Boronic acid compounds as potential pharmaceutical agents

Med Res Rev. 2003 May;23(3):346-68. doi: 10.1002/med.10043.

Abstract

Boronic acid compounds have been used, because of their unique structural features, for the development of potent enzyme inhibitors, boron neutron capture agents for cancer therapy, and as antibody mimics that recognize biologically important saccharides. Consequently, there has been a surge of interests in boronic acid compounds. This study reviews the recent development in this area during the last six years.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Acids / chemistry
  • Acids / pharmacology
  • Boron Compounds / chemistry
  • Boron Compounds / pharmacology*
  • Boron Neutron Capture Therapy
  • Drug Delivery Systems
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • Humans

Substances

  • Acids
  • Boron Compounds
  • Enzyme Inhibitors