Rationale, design, and baseline data for Commit to Quit II: an evaluation of the efficacy of moderate-intensity physical activity as an aid to smoking cessation in women

Prev Med. 2003 Apr;36(4):479-92. doi: 10.1016/s0091-7435(02)00051-8.


Background: Commit to Quit II is a 4-year randomized controlled trial comparing the efficacy of a cognitive-behavioral smoking cessation treatment plus moderate-intensity physical activity with the same cessation treatment plus contact control.

Methods: Sedentary women smokers (n = 217) were randomized to receive 8 weeks of treatment followed by 12 months of follow-up. This article outlines the study design, presents baseline data about the sample, and compares the sample to national samples and to our previous study examining vigorous-intensity exercise as an aid to smoking cessation.

Results: Married and white participants reported significantly higher levels of nicotine dependence than unmarried and minority participants. Higher levels of nicotine dependence were also significantly related to lower smoking cessation self-efficacy and higher levels of self-reported depression, anxiety, and perceived stress. Additionally, participants smoked significantly more cigarettes (mean 20.6) than a national sample of female smokers (mean 16.1). On average, participants were significantly older, weighed significantly more, and scored significantly higher on a measure of anxiety than participants in our previous trial.

Conclusions: Our sample consisted of women who were heavier smokers than national samples seeking treatment. It remains to be determined how this will impact their ability to attain cessation in the present study.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Administration, Cutaneous
  • Adolescent
  • Adult
  • Affect
  • Aged
  • Anxiety
  • Behavior Therapy / methods*
  • Body Weight
  • Combined Modality Therapy
  • Exercise*
  • Female
  • Health Behavior
  • Humans
  • Life Style
  • Middle Aged
  • Motor Activity*
  • Nicotine / administration & dosage
  • Research Design
  • Smoking / drug therapy
  • Smoking / psychology
  • Smoking Cessation / methods*
  • Smoking Cessation / psychology
  • Treatment Outcome


  • Nicotine