Acetaminophen toxicosis in a Dalmatian

Can Vet J. 2003 Feb;44(2):142-4. doi: 10.4141/cjas64-022.

Abstract

An 11-year-old, spayed female Dalmatian was presented with suspected acetaminophen toxicosis. The dog was severely depressed. Methemoglobinemia, facial edema, and hemoglobinuria responded to treatment with intravenous fluids, N-acetylcysteine, ascorbic acid, and sodium bicarbonate. There was no clinical evidence of hepatic damage typical of acetaminophen toxicity in the dog.

Publication types

  • Case Reports

MeSH terms

  • Acetaminophen / poisoning*
  • Acetylcysteine / therapeutic use
  • Analgesics, Non-Narcotic / poisoning*
  • Animals
  • Ascorbic Acid / therapeutic use
  • Dog Diseases / chemically induced*
  • Dog Diseases / therapy
  • Dogs
  • Emergency Treatment / veterinary
  • Female
  • Fluid Therapy / veterinary
  • Free Radical Scavengers / therapeutic use
  • Liver / drug effects
  • Liver / pathology
  • Methemoglobinemia / chemically induced
  • Methemoglobinemia / veterinary
  • Sodium Bicarbonate / therapeutic use
  • Treatment Outcome

Substances

  • Analgesics, Non-Narcotic
  • Free Radical Scavengers
  • Acetaminophen
  • Sodium Bicarbonate
  • Ascorbic Acid
  • Acetylcysteine