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Review
, 5 (2), 169-77

Regulation of Antiviral CD8+ T Cells by Inhibitory Natural Killer Cell Receptors

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Review

Regulation of Antiviral CD8+ T Cells by Inhibitory Natural Killer Cell Receptors

Anthony M Byers et al. Microbes Infect.

Abstract

Recent evidence indicates that CD8(+) T cells express natural killer cell receptors that constrain the range and magnitude of their activities. For virus-specific CD8(+) T cells, upregulation of these receptors serves to control infection, while concurrently minimizing bystander pathology. Dysregulated expression of these receptors, however, may foster the establishment of persistent virus infection.

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