Manic symptoms associated with quetiapine treatment

Eur Neuropsychopharmacol. 2003 Mar;13(2):135-6. doi: 10.1016/s0924-977x(02)00124-4.


This case illustrates the induction of manic-like symptoms in a 26-year-old male patient with DSM-IV paranoid schizophrenia following treatment with quetiapine. The only drug he had received prior to quetiapine was risperidone which was occasionally taken in the previous 3 years. The manic symptoms remitted after quetiapine withdrawal.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bipolar Disorder / chemically induced*
  • Bipolar Disorder / diagnosis
  • Bipolar Disorder / psychology
  • Dibenzothiazepines / adverse effects*
  • Dibenzothiazepines / therapeutic use
  • Humans
  • Male
  • Quetiapine Fumarate
  • Schizophrenia / drug therapy


  • Dibenzothiazepines
  • Quetiapine Fumarate