Update on childhood rhabdomyosarcoma

Arch Dis Child. 2003 Apr;88(4):354-7. doi: 10.1136/adc.88.4.354.


The overall survival of childhood rhabdomyosarcoma has improved dramatically over the past 10 years. Early diagnosis and appropriate referral to a specialised centre leading to an accurate and timely diagnosis reflects on overall outcome. Recent molecular studies have identified different biological subtypes resulting in the recognition of poorer subgroups and allowing more appropriate treatment to be administered. Clinical trials remain the cornerstone to further improve outcome, now carried out on an international basis.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Child
  • Humans
  • Rhabdomyosarcoma / diagnosis
  • Rhabdomyosarcoma / genetics
  • Rhabdomyosarcoma / therapy*
  • Survival Rate
  • Translocation, Genetic
  • Treatment Outcome


  • Antineoplastic Agents