An investigation into the efficacy of Scutellaria lateriflora in healthy volunteers

Altern Ther Health Med. 2003 Mar-Apr;9(2):74-8.


Scutellaria lateriflora is an herbal medicine with long-standing traditional use as a relaxing nervine. There has been controversy in the literature with regards to its efficacy, and this study was designed to clarify its effectiveness in reducing anxiety, one of the phytotherapeutic indications. A double blind, placebo-controlled study of healthy subjects demonstrated noteworthy anxiolytic effects. The use of phytomedicines for the treatment of anxiety is reviewed, as is the published literature on S. lateriflora and its putative toxicity.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Oral
  • Adult
  • Aged
  • Anti-Anxiety Agents / administration & dosage
  • Anti-Anxiety Agents / therapeutic use*
  • Anxiety / drug therapy*
  • Anxiety / pathology
  • Cross-Over Studies
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Manifest Anxiety Scale
  • Middle Aged
  • Phytotherapy*
  • Plant Preparations / administration & dosage
  • Plant Preparations / therapeutic use*
  • Reference Values
  • Scutellaria*
  • Treatment Outcome


  • Anti-Anxiety Agents
  • Plant Preparations