Intracranial hemorrhage in late hemorrhagic disease of the newborn

Indian Pediatr. 2003 Mar;40(3):243-8.

Abstract

This study was conducted to evaluate the clinical profile and outcome in late hemorrhagic disease of the newborn (HDN) with particular reference to intracranial hemorrhage. Infants (n = 42) presenting with late HDN from January 1998 to December 2001 were studied. Majority (76%) were in the age group of 1-3 months. All were term babies on exclusive breast-feeding and none received vitamin K at birth. 71% patients presented with intracranial hemorrhage, commonest site being intracerebral and multiple ICH. Visible external bleeding was noted in 1/3rd of patients only. Three patients expired. Late HDN is still an important cause of mortality and morbidity in developing countries where vitamin K prophylaxis is not routinely practiced. Isolated intracranial hemorrhage is a common mode of presentation.

MeSH terms

  • Female
  • Humans
  • Infant, Newborn
  • Intracranial Hemorrhages / diagnosis
  • Intracranial Hemorrhages / etiology*
  • Intracranial Hemorrhages / therapy
  • Male
  • Outcome Assessment, Health Care
  • Risk Factors
  • Time Factors
  • Vitamin K Deficiency Bleeding / complications*
  • Vitamin K Deficiency Bleeding / diagnosis
  • Vitamin K Deficiency Bleeding / therapy