Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, against PhIP-induced mammary carcinogenesis

Adv Exp Med Biol. 2002:507:371-6. doi: 10.1007/978-1-4615-0193-0_57.

Authors

Toshihiko Kawamori¹, Seiichi Nakatsugi, Toshihisa Ohta, Takashi Sugimura, Keiji Wakabayashi

Affiliation

¹ Cancer Prevention Division, National Cancer Center Research Institute, 1-1 Tsukiji 5-chome, Chuo-ku, Tokyo 104-0045, Japan.

PMID: 12664612
DOI: 10.1007/978-1-4615-0193-0_57

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
Anticarcinogenic Agents / pharmacology*
Carcinogens*
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors / pharmacology
Female
Imidazoles*
Isoenzymes / drug effects
Isoenzymes / metabolism*
Mammary Neoplasms, Animal / chemically induced*
Mammary Neoplasms, Animal / pathology
Mammary Neoplasms, Animal / prevention & control*
Prostaglandin-Endoperoxide Synthases / drug effects
Prostaglandin-Endoperoxide Synthases / metabolism*
Rats
Sulfonamides / pharmacology*

Substances

Anti-Inflammatory Agents, Non-Steroidal
Anticarcinogenic Agents
Carcinogens
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors
Imidazoles
Isoenzymes
Sulfonamides
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
Cyclooxygenase 2
Prostaglandin-Endoperoxide Synthases
nimesulide