Regulation of cell division: stop the SIN!

Trends Cell Biol. 2003 Apr;13(4):159-62. doi: 10.1016/s0962-8924(03)00034-5.

Abstract

A novel mechanism, centered on the Polo-like kinase Plo1p and Dma1p - a protein with a RING finger and an FHA-domain - prevents cytokinesis as long as the spindle checkpoint is active.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Cycle Proteins / physiology*
  • Cell Division / physiology*
  • Genes, cdc / physiology*
  • Humans
  • Protein Kinases / physiology
  • Protein-Serine-Threonine Kinases
  • Proto-Oncogene Proteins
  • Signal Transduction / physiology
  • Spindle Apparatus / physiology*
  • Yeasts / physiology

Substances

  • Cell Cycle Proteins
  • Proto-Oncogene Proteins
  • Protein Kinases
  • Protein-Serine-Threonine Kinases
  • polo-like kinase 1