Occurrence in wild strains of Neurospora crassa of genes controlling genetic recombination

Aust J Biol Sci. 1975 Apr;28(2):213-25. doi: 10.1071/bi9750213.


Each of the main laboratory wild stocks of N. crassa carries one of two alleles at the rec-1 and rec-2 loci and one of three at the rec-3 locus. The constitutions of the stocks are given in Fig. 1. Some of those conserved are evidently not the originals. The third rec-3 gene (rec-3L), found in Lindegren A, controls recombination at the am-1 locus to a level between that of rec-3+ and rec-3, the relative levels being 1 : 8 : 25. At the his-2 locus rec-3L is indistinguishable from rec-3+ in its level of control. This proves that there are minor differences between the control (con) genes, near to am-1 and his-2, which recognize products of rec-3 genes. Further, this is the first clear evidence, though indirect, that the binding sites for products of rec genes are situated in the chromosome regions where recombination is modulated.

MeSH terms

  • Alleles
  • Binding Sites
  • Crosses, Genetic
  • Genes*
  • Neurospora crassa*
  • Neurospora*
  • Pedigree
  • Recombination, Genetic*