Tuberculous meningitis in childhood. Forty-three cases

Am J Dis Child. 1976 Apr;130(4):364-7. doi: 10.1001/archpedi.1976.02120050022004.

Abstract

Forty-three patients in the pediatric age group had tuberculous meningitis. Therapy included the use of adrenocorticosteroids. All four patients who were in stage 1 on admission to the hospital, seven of the 33 in stage 2, and one of the six in stage 3 (coma) recovered without gross neurological sequelas. Eight patients died, and the remaining 23 recovered, with late neurological sequelas. Early diagnosis and appropriate treatment determine the prognosis of tuberculous meningitis.

MeSH terms

  • Adolescent
  • Adrenal Cortex Hormones / therapeutic use
  • Aminosalicylic Acids / therapeutic use
  • Child
  • Child, Preschool
  • Drug Therapy, Combination
  • Female
  • Glucose / cerebrospinal fluid
  • Humans
  • Infant
  • Isoniazid / therapeutic use
  • Male
  • Prognosis
  • Retrospective Studies
  • Skin Tests
  • Streptomycin / therapeutic use
  • Tuberculosis, Meningeal* / cerebrospinal fluid
  • Tuberculosis, Meningeal* / drug therapy
  • Tuberculosis, Meningeal* / mortality

Substances

  • Adrenal Cortex Hormones
  • Aminosalicylic Acids
  • Glucose
  • Isoniazid
  • Streptomycin