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Adolescent Precursors of Cannabis Dependence: Findings From the Victorian Adolescent Health Cohort Study

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Adolescent Precursors of Cannabis Dependence: Findings From the Victorian Adolescent Health Cohort Study

Carolyn Coffey et al. Br J Psychiatry.

Erratum in

  • Br J Psychiatry. 2003 Jul;183:80

Abstract

Background: Dependence increases the likelihood of adverse consequences of cannabis use, but its aetiology is poorly understood.

Aims: To examine adolescent precursors of young-adult cannabis dependence.

Method: Putative risk factors were measured in a representative sample (n=2032) of secondary students in the State of Victoria, Australia, six times between 1992 and 1995. Cannabis dependence was assessed in 1998, at age 20-21 years.

Results: Of 1601 young adults, 115 met criteria for cannabis dependence. Male gender (OR=2.6, P < 0.01), regular cannabis use (weekly: OR=4.9; daily: OR=4.6, P=0.02), persistent antisocial behaviour (linear effect P=0.03) and persistent cigarette smoking (linear effect P=0.02) independently predicted cannabis dependence. Neither smoking severity (P=0.83) nor persistent psychiatric morbidity (linear effect P=0.26) independently predicted dependence. Regular cannabis use increased risk only in the absence of persistent problematic alcohol use.

Conclusions: Weekly cannabis use marks a threshold for increased risk of later dependence, with selection of cannabis in preference to alcohol possibly indicating an early addiction process.

Comment in

  • Evidence in cannabis research.
    Miller P. Miller P. Br J Psychiatry. 2004 Jun;184:542; author reply 543-4. doi: 10.1192/bjp.184.6.542. Br J Psychiatry. 2004. PMID: 15172954 No abstract available.
  • Evidence in cannabis research.
    Palmer T. Palmer T. Br J Psychiatry. 2004 Jun;184:542-3; author reply 543-4. doi: 10.1192/bjp.184.6.542-a. Br J Psychiatry. 2004. PMID: 15211715 No abstract available.

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