Severe solar maculopathy associated with the use of lysergic acid diethylamide (LSD)

Am J Ophthalmol. 1976 Apr;81(4):413-6. doi: 10.1016/0002-9394(76)90295-6.


A 23-year-old man sustained severe macular damage by sun gazing during a hallucinogenic drug-induced state. Sequential fundus photography and fluorescein angiography documented prominent focal injury to the retinal pigment epithelium.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Fluorescein Angiography
  • Humans
  • Lysergic Acid Diethylamide*
  • Macula Lutea*
  • Male
  • Pigment Epithelium of Eye
  • Retinal Diseases / etiology
  • Substance-Related Disorders / complications*
  • Sunlight*


  • Lysergic Acid Diethylamide