Classification of rheumatoid joint inflammation based on laser imaging

IEEE Trans Biomed Eng. 2003 Mar;50(3):375-82. doi: 10.1109/TBME.2003.808827.


We describe a classification system for a novel imaging method for arthritic finger joints. The basis of this system is a laser imaging technique which is sensitive to the optical characteristics of finger joint tissue. From the laser images acquired at baseline and follow-up, finger joints can automatically be classified according to whether the inflammatory status has improved or worsened. To perform the classification task, various linear and kernel-based systems were implemented and their performances were compared. Based on the results presented in this paper, we conclude that the laser-based imaging permits a reliable classification of pathological finger joints, making it a sensitive method for detecting arthritic changes.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Arthritis, Rheumatoid / classification*
  • Arthritis, Rheumatoid / diagnosis*
  • Expert Systems
  • Finger Joint / pathology*
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Lasers*
  • Observer Variation
  • Pattern Recognition, Automated
  • Reproducibility of Results
  • Sensitivity and Specificity