Predicting psychological distress in patients with leukaemia and lymphoma

J Psychosom Res. 2003 Apr;54(4):289-92. doi: 10.1016/s0022-3999(02)00396-3.


This study examines the relationship between coping style, quality of life (QOL) and psychological distress in a sample of patients with leukaemia and lymphoma. Fifty-one consecutive in-patients, day cases and haematology out-patient attenders entered the study and completed a 10-item self-report questionnaire, the Hospital Anxiety and Depression Scale (HADS), the Mental Adjustment to Cancer Scale (MACS) and the Schedule for the Evaluation of Individual Quality of Life (SEIQOL). Fifty-one percent of patients reached caseness for moderate distress. Fourteen percent of patients reached caseness for severe distress. Twenty-seven percent of patients were identified as having adjusted poorly to their diagnosis having low scores on the Fighting Spirit subscale of the MAC and high scores on the Hopeless/Helpless subscale. There was a significant association between patients who scored highly on the HADS and dissatisfaction with the information provided. Use of a logistic regression model showed that those patients most likely to be suffering from severe psychological distress were those with a worse coping style, measured by MAC. The clinical implications of these findings are discussed.

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Aged
  • Attitude to Health
  • Cross-Sectional Studies
  • Depressive Disorder, Major / diagnosis
  • Depressive Disorder, Major / etiology*
  • Female
  • Humans
  • Leukemia / psychology*
  • Logistic Models
  • Lymphoma / psychology*
  • Male
  • Middle Aged
  • Prospective Studies
  • Quality of Life
  • Severity of Illness Index
  • Surveys and Questionnaires