Confirmation of cervical neoplasia using a hand-held, lighted magnification device

Int J Gynaecol Obstet. 2003 Apr;81(1):35-40. doi: 10.1016/s0020-7292(02)00413-7.


Objectives: The objective of this study was to estimate the sensitivity and specificity of visual inspection with acetic acid and magnification (VIAM) using the AviScope device to confirm high-grade cervical intraepithelial neoplasia or carcinoma.

Methods: VIAM was performed on 142 women aged 18-50 years referred to three colposcopy clinics because of abnormal cervical cytology. Each woman then had a colposcopic examination with cervical biopsy when indicated.

Results: The AviScope device identified 24 of the 40 women who had CIN 2, 3, or carcinoma, yielding a sensitivity of 60.0% (95% CI 43.4, 74.7). The AviScope correctly identified 60 of 87 women negative for dysplasia or cancer, yielding a specificity of 69.0% (95% CI 58.0, 78.2) compared with colposcopy and cervical histology.

Conclusion: VIAM using the AviScope device was moderately sensitive and specific for the confirmation of high-grade cervical lesions in women referred with abnormal cervical cytology.

Publication types

  • Case Reports

MeSH terms

  • Acetic Acid
  • Adolescent
  • Adult
  • Colposcopy
  • Female
  • Humans
  • Indicators and Reagents
  • Middle Aged
  • Physical Examination
  • Sensitivity and Specificity
  • Uterine Cervical Dysplasia / diagnosis*
  • Uterine Cervical Dysplasia / pathology
  • Uterine Cervical Neoplasms / diagnosis*
  • Uterine Cervical Neoplasms / pathology


  • Indicators and Reagents
  • Acetic Acid