Abstract
[structure: see text] Two neuraminic acid-based, C-glycoside polymers were synthesized. Preliminary studies on one of these polymers showed potent neuraminidase inhibitory activity, suggesting potential utility as an antipathogenic surface coating for the preparation of antimicrobial biomaterials.
MeSH terms
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / pharmacology
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Clostridium perfringens / enzymology
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Enzyme Inhibitors / chemical synthesis*
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Enzyme Inhibitors / pharmacology
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Glycine max
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Glycosides / chemical synthesis*
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Horseradish Peroxidase / chemistry
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Horseradish Peroxidase / metabolism
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Neuraminic Acids / chemical synthesis*
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Neuraminic Acids / pharmacology
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Neuraminidase / antagonists & inhibitors
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Peroxidase / chemistry
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Peroxidase / metabolism
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Polymers / chemical synthesis*
Substances
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Anti-Bacterial Agents
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Enzyme Inhibitors
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Glycosides
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Neuraminic Acids
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Polymers
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Horseradish Peroxidase
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Peroxidase
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Neuraminidase