DNA Transport During Transformation

Front Biosci. 2003 May 1;8:s544-56.


The ability to take up exogenous DNA is a requisite for genetic competence and transformation. Here we review the process of DNA transport in competent bacteria. Two kinds of machineries have been described. In the first one, the components show similarities to the proteins involved in biogenesis of type IV pili and type II secretion systems. The second one is related to the type IV secretion system and conjugation apparatus.

Publication types

  • Review

MeSH terms

  • Bacteria / genetics
  • Bacteria / metabolism
  • Bacterial Physiological Phenomena
  • Biological Transport, Active / physiology*
  • DNA / genetics*
  • DNA / metabolism*
  • Transformation, Genetic / physiology*


  • DNA