Functional perfusion imaging using continuous arterial spin labeling with separate labeling and imaging coils at 3 T

Magn Reson Med. 2003 May;49(5):791-5. doi: 10.1002/mrm.10438.


Functional perfusion imaging with a separate labeling coil located above the common carotid artery was demonstrated in human volunteers at 3 T. A helmet resonator and a spin-echo echo-planar imaging (EPI) sequence were used for imaging, and a circular surface coil of 6 cm i.d. was employed for labeling. The subjects performed a finger-tapping task. Signal differences between the condition of finger tapping and the resting state were between -0.5% and -1.1 % among the subjects. The imaging protocol included a long post-label delay (PLD) to reduce transit time effects. Labeling was applied for all repetitions of the functional run to reduce the sampling interval.

MeSH terms

  • Adult
  • Carotid Artery, Common / physiology
  • Echo-Planar Imaging
  • Fingers / physiology
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Motor Cortex / physiology*
  • Perfusion / instrumentation
  • Spin Labels


  • Spin Labels